Guido Rodriguez's first-half goal, his first in 11 international appearances, helped Argentina win 1-0 over Uruguay in the Copa América on Friday.
Uruguay had not beaten Argentina in the Copa América since 1989 and they quickly fell behind Rodriguez's header.
The Real Betis midfielder was given a starting berth for the first time since June 2019 and justified that decision when he converted a cross from Lionel Messi after 10 minutes.
The goal gave Argentina all three points and condemned their neighbors to defeat in their Copa América campaign.
The result of a game that was both end-to-end, but lacking genuine enthusiasm in an empty stadium in Brasilia, Uruguay went down to Group A without points combined with Bolivia, having played two and Lost two.
Argentina moved up to joint top spot on four points with Chile, who beat Bolivia 1-0 on Friday. Paraguay have three points from one game.
Striker Edinson Cavani was back for Uruguay after missing the last two games via suspension and produced one of the few memorable moments for his team when he was unfortunate enough to see a loud shout for a penalty in 26 minutes. was.
It was a sign of Uruguay's miserable night that although he had a bit more authority, he never scored a shot on goal throughout the match.
At the other end, Messi caused problems for Uruguay with his dribble in the final third, but Uruguay's defenders often knocked him out of the crowd.
The result extended Argentina's unbeaten run to 15 games since losing the final Copa America in the semi-finals in 2019.
Their next game is against Paraguay on Monday, while Uruguay will take on Chile on the same day.